San Diego Metro Area, CA
This position requires an individual with MS (minimum of 1-2 years of experience) or BS degree (minimum of 4-6 years of experience) in biology with experience in biotech or pharma (or equivalent). Relevant technical skills include: designing and performing cell-based assays, performing dose-response curves with experimental small molecules and/or biologicals, cancer cell signaling analysis using Western blotting or other techniques, multicolor flow cytometry, Q-PCR, MSD (MesoScale), ELISA, and data analysis including appropriate statistical analysis.
Ability to follow laboratory procedures with attention to detail, and successfully execute experiments at the bench and reporting back to supervisor and other project team members (presentations, ELN, study reports).
Proficient in mammalian cell culture
Experience with a variety of cell-based assays (luminescence or fluorescence-based).
Proficient in the use of lentiviral transduction and/or plasmid-based transfection methods.
Experience with gene expression analysis (e.g. Q-PCR)
Experience with biomarker assay development (e.g. immunohistochemistry, flow cytometry, MSD).
Familiar with application of multicolor flow cytometry techniques and analysis.
Proficient in the use of data management tools and software for analyzing data sets from various assay formats (FlowJo, GraphPad Prism, Microsoft Office Suite).
Familiar with calculating IC50 values and other parameters from dose-response assays.
Good understanding of cancer biology, molecular biology and cell biology (solid tumors and/or hematological malignancies).
Excellent organization, communication and presentation skills.