Oligonucleotide Scientist

San Francisco Metro Area, CA

Job Type: Scientific Job Number: JN -052024-32458 Region: San Francisco Metro Area

Job Description

R&D Partners is seeking to hire an Oligonucleotide Scientist II in South San Francisco, CA.

Your main responsibilities as an Oligonucleotide Scientist II:

The candidate will work in an oligonucleotide therapeutic drug discovery research lab and interface across different therapeutic areas, including neuroscience, immunology and oncology, to help build a comprehensive therapeutic discovery strategy.

Good understanding and also troubleshooting experience in oligonucleotide synthesis, impurity profiling is a plus.

Collaborate with other scientists to maintain common lab equipment such as oligo synthesizers, HPLC and desalting units.

Perform literature reviews, propose, and execute nucleic acid chemistry plans, coordinate chemistry and biology data to support oligonucleotide compound progression.

Establish methods for scaled-up synthesis of lead molecules and coordinate material delivery for preclinical studies.

What we are looking for in an Oligonucleotide Scientist II:

The qualified individual will possess a BS/MS in Organic Chemistry or related discipline.

The candidate must have hands-on experience in oligonucleotide synthesis using automated oligo synthesizers, novel nucleic acid chemistry, oligonucleotide purification and characterization using HPLC and mass spectrometry.

The pharmaceutical or biotechnology industry experience in research and development of RNAi therapeutics is preferred.

A good understanding of nucleic acid therapeutic modalities, modification chemistries, sequence selection, and mechanism of action is preferred.

Relevant experience in oligonucleotide therapeutics, large molecule drug discovery, oligonucleotide delivery or bio-conjugation is desirable.

Why Choose R&D Partners?

As an employee, you have access to a comprehensive benefits package including:

Medical insurance PPO, HMO & HSA

Dental & Vision insurance

401k plan

Employee Assistance Program

Long-term disability

Weekly payroll

Expense reimbursement

Online timecard approval

Pay Scale:

$61,963 $98,077 (Dependent on Experience)

R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.

R&D Partners is an equal-opportunity employer.


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