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Senior Research Associate, Upstream Process Development

Marin Metro Area, CA

Post Date: 03/01/2018 Job ID: JN -032018-21047 Job Type: Scientific
The Cell Culture Process Development department is seeking to fill a temporary position for an experienced Research Associate in upstream research and development. The successful candidate will work both independently and as part of a team focusing on optimizing production of recombinant viral vectors for the company s gene therapy program.

  • Broad technical proficiency in cell culture and upstream process development preferably in an industrial laboratory
  • Critical thinking, data analysis and interpretation skills
  • Insect cell culture and baculovirus expression system
  • AAV viral vector production
  • Downstream processing; experience with protein chromatography
  • Analytical assays: qPCR, ddPCR, ELISA, electrophoresis, Western blot, cell-based assays
  • Knowledge of stirred-tank bioreactor operation is a plus
  • Minimum: Bachelor s degree in biological sciences or in a related field with five years of experience in a cell culture laboratory.
  • Preferred: Bachelor s degree with 5+ years or Master s degree with 2+ years of experience in industrial upstream process development
  • Cell line maintenance, expansion, infection
  • Production, harvest, and purification of the viral material
  • Perform associated analytical assays
  • Diligently document the results
  • Maintenance of laboratory equipment
  • Flexibility in a fast-paced, changing environment; be willing to accept responsibilities outside of the initial job description
  • Handle multiple tasks efficiently
  • Closely interact with other team members; develop internal and external collaborations
  • Present results and conclusions in group and department meetings

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