Scientist - Protein Development
Newark Metro Area, NJ
BS/MS/PhD degree in Pharmaceutical/Biological Sciences, or relevant scientific discipline with relevant industrial experience in drug product development of therapeutic protein products
- Drug product formulation and process development of protein therapeutics such as fusion proteins, monoclonal antibodies, and bi-specific antibody variants
Understanding and hands-on experience with common analytical techniques used for protein characterization such as protein concentration measurement, size exclusion chromatography (SEC-HPLC), ion exchange (IEX-HPLC), reverse phase (RP-HPLC), isoelectric focusing (IEF) and subvisible particle analysis.
Working knowledge of various biophysical techniques (DSC, DSF, CD, DLS) in protein formulation development is preferred.
Scientific background and hands-on experience with common lab procedures used during protein formulation/process development studies including preparation of buffer and excipient stock preparation under clean room / sterile conditions, and performing buffer exchange, filtration, filling operations etc.
Basic understanding of protein structure, stability and degradation mechanisms is preferred.
- Ability to review scientific literature and write protocols and technical reports