Newark Metro Area, NJ
Responsibilities of the Mass Spectrometry Scientist will include, but are not limited to, the following:
Carry out Mass Spectrometry-based method development, method validation, and sample analysis with minimal supervision. Where required, perform experiments in accordance with cGLP/cGMP regulations, established business processes and protocols, and applicable SOPs.
Perform elemental impurity testing using ICP-MS and ICP-OES instrumentations.
Develop and validate LC/MS and GC/MS based trace analysis methods for quantitation of potentially mutagenic (genotoxic) impurities in complex sample matrices.
Perform impurity identifications by LC/MS and NMR techniques.
Document laboratory work that is detailed, timely and in compliance with cGLP/cGMP requirements
Conduct technical data reviews, and present data interpretation and conclusions to customers for making informed decisions.
Explore and implement innovative mass spectrometry methodology and procedures for analytical problem-solving and to improve analytical results and process efficiency.
Mentor and train others in various mass spectrometric techniques.
Proven expertise in various mass spectrometric techniques: LC/MS, GC/MS, ICP/MS.
Proficient in wet chemistry sample extraction techniques, modern chromatographic separations (HPLC, GC), and preparative chromatography for impurity isolation.
Extensive hands-on experience with MS based quantitative method development and validation.
Demonstrated expertise in identification of impurities and degradation products in pharmaceutical products mass spectrometry and NMR spectroscopy.
Demonstrated experience in elemental impurity testing using ICP-MS and ICP-OES.
A demonstrated record of scientific accomplishment, laboratory experimentation, publication and presentation especially in mass spectrometry.
Strong problem-solving and troubleshooting skills including experimental design and execution.
Ability to work independently, and to present analytical results and conclusions to customers.
Graduate training (M. S. or Ph.D.) is preferred