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Scientist, Antibody Discovery

San Mateo Metro Area, CA

Posted: 09/19/2019 Job Type: Scientific Job Number: JN -092019-25647

We are seeking a creative Scientist with a strong background in cellular assay development and molecular biology to develop new screening assays to enable therapeutic antibody discovery, optimization and characterization. This role will coordinate closely with our biophysical/biochemical assay development scientists, our antibody discovery scientists and project teams to also help with new target validation and antibody developability activities. This role has great career advancement potential with leadership opportunities and will report to the Associate Director of Antibody Discovery.


  • Design, build and develop cellular assays to support antibody discovery and new target selection
  • Support screening and characterization activities during antibody discovery, to enable preclinical development of lead assets
  • Present results, interpretation and next steps at research team meetings


  • Ph.D. with 1+ years of industry experience or 3+ years of postdoctoral studies
  • Record in designing and establishing novel cell assays to measure activities such as signaling, metabolism, enzymatic activity, endocytosis, and/or transport; aseptic maintenance of cell lines and primary cells; proficiency in cellular manipulation such as transfection, electroporation, lentiviral infection, microscopy, CRISPR, and/or siRNA/shRNA knockdown
  • Deep experience in molecular biology (reporter) construct design, site-directed mutagenesis, PCR, cloning, sequencing
  • Experience with techniques such as ELISA, MSD, FACS, Western Blot
  • Highly motivated, innovation-focused, independent individual
  • Highly collaborative and effective with multi-tasking
  • Excellent communication skills
  • Thrives in a fast paced and dynamic team environment; fast learning and adaptable
  • Desirable skills: experience with NGS, antibody-based cellular screening, management of CROs, understanding of cancer immunology
  • Proficiency with software for DNA sequence/vector analysis, graphical data analysis, FACS plots, for example: VectorNTI, Sequencher, GraphPad Prism, FlowJo
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