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Scientific Associate

Raleigh Metro Area, NC

Post Date: 07/20/2018 Job ID: JN -072018-22097 Job Type: Scientific
Description:
Support Downstream Technical Development projects, including developing, defining, and implementing purification processes; driving continuous improvements; and providing commercial support for influenza vaccine production.

Major Accountabilities:
  • Independently operate small scale bioprocess equipment, including filtration, TFF, centrifugation, and column chromatography systems.
  • Continually and independently educate oneself on the correct operation and maintenance of laboratory bioprocess equipment used for protein purification.
  • Collaboratively design and execute small scale experiments to define and characterize bioprocess steps.
  • Work and thrive under tight deadlines on projects of varying size, demonstrating awareness of broader project objectives.
  • Perform analytical testing (e.g., SDS-PAGE) to characterize/quantify vaccine antigens and contaminants.
  • Understand and interpret experimental data and results to support decisions and understanding of purification processes.
  • Understand and apply bioprocess scale-up strategies.
  • Communicate (present, write-up in technical documents, etc.) results to colleagues and project teams.
  • Solve complex problems using analytical thinking gained through formal education and previous roles.
  • Function effectively as a member of a collaborative team.
  • Prepare and maintain laboratory equipment, instruments, and raw materials.
  • Prepare experimental protocols, reports, and work instructions.
Skills:
  • Knowledge of bioprocess unit operations (e.g. bioreactors, chromatography, filtration) and engineering scaling principles
  • Experience with GE AKTA chromatography systems/Unicorn software and lab/pilot scale TFF systems is desired
  • Demonstrated knowledge of / expertise with analytical methods (e.g., SDS-PAGE, Western Blot, HPLC, ELISA, PicoGreen) is a plus
  • Knowledge of GMPs preferred
  • Ability to work with cross functional teams
  • Strong communication skills, technical writing ability, and good attention to detail
  • Must be a self-starter and able to work with minimal supervision
  • Bachelor s Degree in related scientific or engineering field with 2 5+ years related industrial or academic experience.
    Master s Degree in related scientific or engineering field with 0 2+ years related industrial or academic experience


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