Newark Metro Area, NJ
The candidate will work with our translational development team and independently contribute to the development and execution of laboratory experiments to understand the activity of compounds and drug combinations. This will include working with multiple myeloma cell lines and immune cells derived from healthy donors and multiple myeloma patients. The candidate should have enthusiasm for helping support clinical programs, have knowledge of immuno-oncology and signal transduction pathways and technical expertise in flow cytometry and molecular based assays documented by relevant publications and work experience. They should also possesses a strong understanding of the science behind ongoing experiments: the rationale, purpose and appropriate analytical methods to aid experimental design, troubleshooting and result interpretation.
A Bachelor s degree in the Life Sciences with 6+ years of hands-on research experience or Master s degree with 3+ years experience in a research environment
Experience with multi-parameter flow cytometry, tissue culture and working with PBMCs a must.
Proficient with general skills of molecular cell biology, such as RNA isolation, RT-PCR, Western Blotting, ELISA/Luminex, and basic cellular assays (e.g. proliferation/apoptosis).
Expierence in isolating T-cells and NK cells from PBMCs a plus.
Experience with PowerPoint, FlowJo and GraphPad Prism software
Communication and writing skills necessary to effectively convey data and interpretations with internal groups and at external meetings.
Problem solving skills to resolve technical issues.
Ability to manage time efficiently to meet project team deadlines and exhibit flexibility and adaptability to changing projects, work assignments and priorities.
Solid understanding of scientific mechanisms and experimental techniques, with knowledge of signal transduction, immunology, cancer cell biology, drug discovery and translational medicine a plus.