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Research Associate II, Bioanalytical

Marin Metro Area, CA

Posted: 06/06/2019 Job Type: Scientific Job Number: JN -062019-25040
RESPONSIBILITIES
  • Develop a variety of analytical methods to detect drug, antibodies to protein therapeutics, and biomarkers in biological matrices. Techniques may include but are not limited to:
    • Protein purification/chromatography
    • Nucleic acid extraction
    • Droplet digital and quantitative polymerase chain reaction (PCR) assays
    • Western blot assays
    • Enzyme-linked immunosorbent assays (ELISA)
    • Electrochemiluminescence assays (ECLA)
    • Enzyme activity and cell-based assays
  • Qualify selected assays or reagents for transfer to BioAnalytical Testing and validation.
  • Analyze data, including basic statistical and graphical analysis.
  • Present results, conclusions, and implications to the BioAnalytical Sciences group.
  • Participate in external scientific meetings and contribute to original peer-reviewed publications.
EXPERIENCE / EDUCATION
  • Bachelors degree in a scientific discipline or equivalent with 2-4 years experience with assay development and validation, or Masters degree with 1-2 years experience working with immunoassays, biomarker assays, or other analytical methods.
  • Working knowledge of cell biology and biochemistry.
  • Excellent verbal and written communication skills.
SUMMARY
BioAnalytical R&D develops analytical methods for detection of drug, antibodies to protein therapeutics, and biomarkers in biological matrices from non-human and human subjects to support projects through multiple stages of development. The Research Associate II (RA II) will design and execute technically complex experiments to support these projects. They will provide quantitative data analysis, interpretation of results, and contribute to technical reports (e.g. assay qualification and validation reports, SOPs). The RA II evaluates complex methods and technologies, identifies new areas requiring process improvement and adapts existing processes or develops new ones with direct input and supervision from a manager. The RAII also evaluates new lab equipment, recommends vendors, and provides assistance to assay development, troubleshooting, and validation. They may contribute to scientific publications and regulatory submissions as required.
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