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Research Associate / Sr. Research Associate, Biology

San Francisco Metro Area, CA

Posted: 10/09/2018 Job Type: Scientific Job Number: JN -102018-22780
The qualified candidate will join a team focused on oncology target discovery and drug discovery efforts. In this position you will support these efforts by providing biology expertise and services including but not limited to the following

  • Culture a variety of cancer cell lines and primary cells
  • Identification and functional assessment of therapeutic targets through RNAi and gene editing techniques
  • Determine the mechanism of action of molecules utilizing:
    • Flow Cytometry
    • Western Blot
    • qPCR
    • Proliferation and Apoptosis assays
  • Execute biological assays (biochemical and cell-based)
  • Perform data analysis, reporting and integration with GraphPad Prism, Microsoft Office and other computer programs
  • Contribute to or lead lab management activities

  • BS or MS in biology, molecular biology, cell biology or related discipline.
  • Proficiency in cell culture and generation of stable cell lines through viral transduction, conditional gene knockdown/expression
  • Proficiency in DNA and RNA isolation and qPCR
  • Experience with protein analysis:
    • Western Blot
    • Flow Cytometry
    • ELISA
    • Immunohistochemistry
  • Experience with enzymatic assays and cell-based assays
  • Excellent computer skills combined with data analysis
  • Must be detail oriented, well organized, and have strong communication skills

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