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Research Associate - Assay Development

San Mateo Metro Area, CA

Posted: 05/18/2018 Job Number: JN -052018-21634

The Research Associate is within the Assay Development and Bioanalytics group. In support of gene therapy drug products in preclinical and clinical development. The candidate will primarily develop, optimize and help qualify ELISA, enzyme activity, and immunogenicity assays, possibly including cell-based assays. The candidate will work collaboratively with different research and development departments to evaluate and implement new assay formats and/or technologies. In addition, the candidate will be expected to perform some testing as needed in support of product characterization. Responsibilities will also include routine lab maintenance, writing test procedures, SOPs, protocols, technical reports, and summarizing/presenting data at internal and external meetings. Maintaining good documentation is required.

Position Qualifications:

  • Minimum of a Bachelor s degree (preferably a Master s) in Biomedical Science, preferably with 2-3 years experience working in a biotech company
  • Broad knowledge base in molecular biology or protein work, biochemistry, and gene therapy
  • Background in the area of retinal or genetic diseases is desired and understanding of AAV biology is a plus
  • Publication in a peer-reviewed journal or having presented at a conference is desired
  • Experience in qualification/validation of quantitative assays is desired
  • Experience in assay development is desired
  • Expertise in a variety of laboratory techniques such as ELISA, cut-point immunogenicity assays, recombinant DNA technology (cloning, transformation, qPCR, DNA/RNA isolation and analysis) sterile tissue culture techniques (transfection, transduction, maintaining cell lines); biochemical techniques such as Western Blot, flow cytometry, and immunofluorescence
  • Experience in tissue handling is preferred
  • Detail oriented and with time management skills
  • Must be proactive, co-operative, and willing to work in a small team environment
  • Excellent verbal and written communication skills
  • Proficient with MS Office and other commonly used software
  • Knowledge of SoftMaxPro and GraphPad Prism a plus
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