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PhD - Cellular Biotherapeutics

San Diego Metro Area, CA

Posted: 08/02/2018 Job Type: Scientific Job Number: JN -082018-22200
Ph.D. degree in molecular, cellular, or immune biology related discipline to participate in research programs developing targeted therapeutics.
The qualified candidate will have solid molecular and cell biology skills and experience in antibody based drug discovery with 2+ years of productive research or industry experience at the postdoctoral level, as evidenced by an appropriate publication record.
Relevant skills include:
Designing and performing cell-based assays, cytokine analysis, and fluorescent imaging
Broad proficiency with multi-parameters flow cytometry (surface/intracellular staining, cell viability) using BD Canto, Celesta, or Attune.
High proficiency with using FlowJo, Prism, Microsoft office applications for data analysis
Experience with primary cell tissue culture and generation of stable overexpressing cell lines
Proficiency in molecular biology laboratory techniques (i.e. cloning, transformations, transfections, Western blotting, ELISAs, and gene reporter systems
Strong background in antibody-based drug discovery with scientific expertise in molecular and cellular biology. Understanding of innate immunity and macrophage biology is strongly desired.
The focus of this position will be to utilize broad in vitro cellular techniques to support ongoing drug discovery, development candidate(s), and their biological mechanisms of action. The successful candidate will be responsible for validating potential drug target(s) for discovery campaigns, screening novel biotherapeutic drug candidates, and conducting primary immune cell-based functional assays for lead evaluation.

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