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Organic Chemist - Associate Scientist

Oakland-Fremont-Pleasanton Metro Area, CA

Posted: 03/21/2018 Job Number: JN -032018-21182

Key Responsibilities:
  • Design and synthesize protein conjugates and novel reagents for in vitro diagnostic medical device products, including drug derivatives, linker arms enzyme conjugates, and immunogens
  • Synthesize and purify compounds involving multistep synthesis from milligram- to multi-gram scale
  • Plan and execute multiple reactions simultaneously
  • Interpret and properly document results of various experiments and present the data at group meetings
  • Conduct, direct and troubleshoot potentially highly complex technical experiments to achieve department and company goals
  • Perform other responsibilities to support the needs of the department as assigned
  • Follow Good Laboratory Practices (GLP) and good documentation practices including lab notebook, MPIs, SOPs and other necessary documentation
  • Comply with Design Controls, Good Manufacturing Practices (GMP) and International Organization for Standardization (ISO) guidelines, which includes, for example, process validation
  • Work independently with little supervision
  • Thorough documentation of experimental procedures - writing of reports and technical documents
  • Achieve a high level of productivity in the laboratory setting, as well as being able to demonstrate the ability to resolve key project hurdles and assumptions by effectively using available information and technical expertise
  • Maintain a safe, pleasant and efficient working environment.
Minimum Requirements/Qualifications:
  • BS (10 + years of experience) or MS (5+ years of experience) or a Ph.D (2+ years of experience) in Organic Chemistry
  • Requires in depth knowledge of Organic Chemistry synthesis and purification of organic reagents, chromatographic and spectroscopic analysis, documentation of results and procedures
  • Must be able to work under pressure and coordinate numerous activities with a multi-disciplinary team of scientists who need to communicate and cooperate to achieve maximum efficiency
  • Excellent written and oral communication skills
  • Excellent organization and strong project management skills
Preferred Experience:
  • Experience as a synthetic organic or medicinal chemist in an industrial laboratory is preferred
  • Candidates must possess a strong background in the theory and practice of synthetic organic chemistry, possess excellent problem solving skills and demonstrate a thorough understanding of synthetic methods and reaction mechanisms
  • Experience in drug conjugates synthesis and techniques
  • Must be able to independently prioritize own work assignments, and consistently demonstrate the ability to perform assigned tasks through rigorous data collection and applying analytical tests and instrumentation in the laboratory
  • Must have expertise in the purification and characterization of organic compounds using applicable modern techniques
  • Self-motivated, independent, team player and a proactive driving force of efficient execution
  • Capable of multi-tasking and changing priorities caused by time, markets, customers, budget or other constraints
  • Proficient in the use of Excel, Powerpoint, ChemDraw and Scifinder
  • Experienced in the use of HPLC, LCMS, Automated purification systems, and UV-VIS
  • Proficient in the interpretation of NMR data
  • Experience working in a GMP environment

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