Mammalian Tissue Culture- Assoc. Scientist
San Diego Metro Area, CA
Must have Mammalian tissue Culture experience and strong Molecular Biologyknowledge
Previous hands-on experience in mammalian cell culture is required.
Various molecular and cellular technologies including, but not limited to, quantitative PCR, protein assays (western, ELISA) is strongly desired. Lenti virus experience and manipulation/editing of gene/message/protein via RNAi and/or CRISPR methods is a plus.
Seeking Exepreinced Associate Scientist to support Solid Tumor Discovery in the Protein Homeostasis development team.
Focuses on delivering novel cancer therapeutics by engaging E3 ubiquitin ligases for targeted protein degradation.
Supporting tissue culture and molecular biology in drug discovery.
The successful candidate will work collaboratively in a multi-disciplinary environment to 1) execute cellular assays to support discovery of small molecules as clinical development candidates; and 2) execute molecular biology studies that further our understanding of the mechanisms of novel compounds. Responsibilities include maintaining patient derived cell lines in addition to conducting cell assays working with novel and standard of care compounds. Performing molecular biology assays investigating gene and protein expression and modulation. The successful candidate will work within discovery project teams and with other scientists across different functional areas and may be expected present results to the group.