San Diego Metro Area, CA
We are seeking an experienced in vivo research associate to support the discovery and development of new drugs for oncology and immune-oncology indications. Ideal candidates must be skilled in animal handling (mice) including drug administration by multiple routes, tumor implanting and tissue harvesting land have extensive in vitro studies experience in the area of immunology and oncology.
The successful applicant will have a strong background in in vivo techniques employed for oncology studies such as tumor inoculation in subcutaneous and orthotopic sites including intracranial inoculations. Applicant should be able to design and execute a variety of in vitro assays primarily with immune cells and cancer cell lines. Successful candidate must be have hands-on experience with ELISAs, mesoscale, western blots, isolating DNA/RNA and qPCR. The successful candidate will have the opportunity to work closely with discovery project teams and scientists and to present his or her work at project team meetings and to the senior research leadership. Industry experience is preferred but not essential.
1. Bachelor s degree with 4 years industry experience or Master s degree in Cell Biology, Cancer Biology, Molecular Biology or Immunology with 2 years industry experience.
2. Extensive experience with vivo studies that include measuring tumors, dosing animals (po, ip and iv), blood sampling, minor surgical procedures , tissue harvesting and tumor inoculations.
3. An understanding of basic T-cell biology and general immunology.
4. Expertise with a variety of cell-based assay technologies including antibody-based detection methods (e.g. Western, ELISA, MSD, Luminex, immunoprecipitation), cell imaging (immunofluorescence) and qPCR.