Associate Scientist - Cell Based Assay Development
San Diego Metro Area, CA
- Responsibilities will include, but are not limited to, the following:
Independently design and conduct cell-based, biochemical and immunoassay development with minimal supervision.
Maintain and characterize various cancer cell lines to support drug discovery.
Perform compound profiling studies using in vitro assays, import and organize data in database, and report results to the supervisor and the project team.
Use automation and perform assay miniaturization to increase throughput of cell-based assays, perform moderate to high throughput screening of compound library and validate hits for SAR studies.
Process and analyze large and complex data sets, report results in a well-organized and easy-to- interpret manner.
Support MoA studies to enable the project team to identify lead candidates, help design in vivo efficacy studies and understand potential toxicological liabilities.
BS/MS in Molecular Biology or related with 4 - 7 years of industrial experience in a drug discovery setting.
Previous industrial experience in drug discovery is required.
Strong molecular and cell biology experience
Familiarity with various cellular assays in high-throughput formats and automation equipment - HTS.