Boston Metro Area, Massachusetts
Responsibilities will include, but are not limit to, the following:
Provides direct on-site early formulation development support to enable efficacy, PK, and toxicology studies for small molecule Drug Discovery efforts.
Provides drug substance characterization including crystallinity assessment, solubility determination, and physicochemical stability evaluation.
Offers solubility enhancement of poor water soluble compounds by applying various solubilization techniques.
Develops understanding of the impact of physiochemical and solid state properties on drug candidate performance.
Perform in-silico biopharmaceutical evaluation to support drugability assessment.
Inform and influence drug discovery team finding new chemical entities with desirable physicochemical and biopharmaceutical properties.
Recommends potential clinical formulation to the project team based on physicochemical and biopharmaceutical properties of the drug candidate.
Demonstrated experience in discovery and preclinical support, preformulation screening, solid state characterization and aiding formulation design.
Sound knowledge of pharmaceutical research and development process.
Good written and verbal communication skills.
M.S./Ph.D.(preferred) in pharmaceutics, pharmaceutical science, pharmaceutical chemistry or related scientific discipline required.
Minimum of 1 to 2 years experiences in pharmaceutical industry in drug discovery and development.
1 to 2 years of relevant experience in discovery and preclinical support, preformulation screening, early formulation development, solid state characterization, and development in the pharmaceutical industry.
Excellent communication, interpersonal skill to collaborate with others on projects.
Minimum MS degree in Pharmaceutics, pharmaceutical science, pharmaceutical chemistry or related scientific discipline required. Advanced degree preferred.