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Scientist - Immuno-oncology

Wayne Metro Area, New Jersey

Post Date: 06/02/2017 Job ID: JN -062017-19185
  • PhD in Immunology or Cellular & Molecular Immunology or Cellular & Molecular Biology, with 2+ years post-doc experience
  • Demonstrated expertise of a wide range of in vitro cellular and biochemical assays, including cell isolation and culture, molecular biology, cellular immunology assays and familiarity with in vivo models of immune disease or oncology are required
    Experience in immune based and/or cell based therapy development preferred.
    Track record of success as evidenced by a strong publication record, and/or, evidence of sustained contributions in the biopharmaceutical industry
    Proven track record of scientific approach to complex problem solving, able to anticipate problems at project level and interpret contingency plans, identifies solutions and strategies, and implements appropriate scientific actions
  • Description:
  • Under the minimal direction of Sr. Director R&D, the Research Scientist will be responsible for performing the laboratory based studies to generate the preclinical PoC datasets
    Support the candidate development and enable IND submissions for next generation of cell-based immune therapies.
    By employing state of the art gene editing techniques (such as CRISPR-mediated genome editing, viral vectors based genetic modification) and various mammalian expression systems, the candidate will define novel cell types for therapeutic candidate development.
    The successful individual will demonstrate subject matter expertise, deep scientific knowledge/execution drive, and the ability to critically evaluate scientific data required to move projects forward.
    The successful candidate will be responsible for experimental data generation and analysis, interpretation and documentation, including regular report and paper generation, presentation of research progress, both written and oral.
    Key member of the team responsible for the development of novel, disruptive cellular immunotherapy concepts and next generation of cellular therapy product candidates, based on the existing proprietary Cellular Therapeutics platforms.
    Design and implement experiments, perform data analysis and interpretation for the discovery and development of novel cell based cancer immunotherapeutics.
    Generate the preclinical PoC, go/no-go decision and IND enabling datasets for novel cell based immunotherapy candidates.
    Maintain cutting edge knowledge and provide expertise in all scientific and technical areas relevant for the discovery and development of cell-based immunotherapeutics.
    As a scientifically rigorous innovator, contribute novel ideas and provide solutions for the achievement of R&D objectives.
    Provide written and oral scientific progress reports to the Sr. Director, Executive Management, generate scientific publications and intellectual property applications, as required.
    Maintain laboratory records and electronic files to support experimental studies and intellectual property development.

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