San Diego Metro Area, California
This Associate Scientist will be part of the Protein Homeostasis Translational team. The successful candidate will have a broad understanding of molecular cell biology and immunology, with unique expertise in small molecule drug development for therapy of various hematology/oncology diseases. The incumbent is responsible for addressing questions of drug scheduling, supporting patient selection hypothesis and developing clinical assays using current techniques and primarily in vitro and ex vivo methods; and is responsible for experiment design, execution and data interpretation for well-defined projects. This employee will keep good data records and write reports.
Specific responsibilities will include, but are not limited to, the following: 1. perform in vitro and ex vivo assays for testing lead compounds in a various type of cells; 2. analyze, interpret and report experimental results; write status reports and non-clinical pharmacology study reports; 3. interface with computational biologists to analyze genomics data for supporting translational activities of Celgene drugs in development
Candidates will be able to conduct experimental protocols with minimal supervision and analyze and troubleshoot experiments.
He/she should demonstrate experience with molecular biology techniques (RT-PCR, siRNA/shRNA transfections, tumor cell signaling analysis), tissue culture, immunoassays, flow cytometry, western blotting and functional assays (cell cycle, apoptosis, etc.).
Candidates should be proficient in Microsoft Word, Excel, statistical programs; have exceptional organizational and communication skills; and ability to accurately document activities.
He/she should flexible and adaptable to changing projects and work assignments
A Master s degree in life sciences with at least 4 years of work experience in the biotech or pharmaceutical industry, preferred.
A B.S. degree in a scientific discipline with at least 6 years of industry experience is also acceptable.