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Associate Scientist (Biotherapeutics)

San Diego Metro Area, California

Post Date: 06/28/2017 Job ID: JN -062017-19404
Description:
Antibody/protein engineering by rational design and/or display (phage or yeast)
Molecular biology, mammalian cell culture and protein expression
Purification of antibody and protein biologics
Functional assays including SPR, ELISA, and FACS
Data presentations and updates in the project team meetings
Providing technical solutions to anticipated problems

Skills/Knowledge preferred:

B.S. in protein sciences, biochemistry, life science or related fields and at least 6 years of research
experience in antibody/protein discovery
Design, plan and execute scientific experiments with minimal supervision
Antibody/protein engineering, purification and characterization such as SDS-PAGE, immunoblotting, analytical SEC, and endotoxin testing/remediation
Antibody/protein interaction assay development by SPR, immunoprecipitation, and ELISA
General assay development for hit-to-lead identification and characterization
Ability to organize data into power point slides for presentations at project/departmental meetings
Excellent notebook keeping, and familiarity with data retrieval and input from a database
Excellent troubleshooting abilities

Skills/Knowledge in one or more of the following areas are a plus:

Basic antibody/protein structure and constructs
Gene cloning and expression
Fluorescence-activated cell sorting
Other display technologies for antibody/protein discovery and optimization,(e.g: yeast or phage display)
Additional expression systems such as bacteria, yeast and baculovirus/insect cells

Functional/Scientific/Technical Skills:

Ability to work independently as well as in a multi-discipline team environment
Ability to multi-task and change priorities based on departmental needs
Ability to embrace a culture of continuous learning and improvement and refining technical skills
Take a proactive role in growth and scientific development
Improve own functional area

Discretion/Latitude:
Develop strategies
Accountable for success of strategies
Provide input to develop cross-functional policies

Creativity and Problem Solving:

Able to anticipate problems at project levels
Recognize risk and propose contingency plans
Anticipate the need for contingencies and develops alternative strategies

Teamwork and Influence:

Communicates within the larger organization
Develops constructive relationships across the organization to achieve company and individual goals and take on leadership roles on cross-functional/divisional teams

Organizational Impact:

Impact is achieved through leading workgroups and contributing to cross-functional teams

Behavioral Competencies:

Champions change and Leads courageously
Networking
Provides directions
Thinks strategically

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